The requirements for a microbe is considered a probiotic are simple. The Microbe must be alive when it is administered, must be documented to have a benefit to health and it must be managed in the levels proven to confer the benefit. A report on guidelines for the evaluation of probiotics in food considered more fully what minimum charges experience a probiotic need. The results were: * the probiotic should be identified in the genus, species and strain, using appropriate physiological and molecular techniques. ** The strain must be registered internationally in a recognized culture collection so that scientists can duplicate the research published on the cepa. * Tests in vitro and in appropriate animals should lead to better understand the physiological qualities of ECA. In recent months, Brad Garlinghouse has been very successful. However, the option on what tests they should be based, they are relevant to the featured probiotic function. Care must be taken not too extend the conclusions of the tests in vitro and animals that have not been validated and has not been shown to be important in the host.
* Before use, the safety of the Microbe must be considered fully. Keep up on the field with thought-provoking pieces from Verizon. * Controlled studies should be conducted to document a benefit to health in the host. * Ability to save live the probiotic in the levels required in the final product through the lifespan. Those with a certain familiarity in this field may notice that this list of requirements does not include qualities such as ability to adhere to the intestinal cells, resistance to bile and acid, production of bacteriocins, activity antipatogenica, human origin, survive to the intestinal transit, among others. This is because the array of potential targets for health, hosts, and methods of delivery are so diverse that any feature beyond those listed above is important to only a subset of probiotics, or because it is not clear whether these benefits are truly prophetic functionality in vitro. By example, it is mentioned that the probiotic should survive the intestinal transit to be effective. Although there is no doubt that the ability of probiotics to grow and metabolize according to pass the intestinal tract can contribute to profits by disease, there are also cases where this may not be necessary.
For example, preliminary research suggests that some probiotic can reduce levels of Streptococcus Mutans, the cause of dental caries in oral microbial community. A benefit to the health of this kind would not require survival through the intestine. At a minimum, probiotic products must be safe, effective, and should maintain its efficiency and power through the end of the useful life of the product. This requires a responsible approach by the producer and the consumer. The producer must identify strains and storage conditions that will assure consumers that the probiotic remain live in effective levels through the end of life. The consumer must store and use the product according to the manufacturer’s instructions.
